Edward S. Connolly, MD

Chair, Neurosurgery

About Me

Dr. Connolly serves as the Byron Stookey Professor and Chair of the Department of Neurological Surgery at Columbia University Vagelos College of Physicians and Surgeons and the Surgeon-in-Chief of the New York Neurological Institute and the New York Presbyterian Hospital – Columbia University Irving Medical Center. He is also the Surgical Director of the Neuro-Intensive Care Unit, caring for patients suffering from the acute effects of both hemorrhagic as well as ischemic stroke.

Working as part of an extremely experienced and world-renowned team of critical care and stroke neurologists, as well as interventional radiologists, endovascular neurosurgeons, neuro anesthesiologists, and specialized nurse practitioners, he provides highly personalized, state-of-the-art care for patients with brain aneurysms, arteriovenous malformations, spontaneous hemorrhages, as well as for those patients with carotid stenosis, moyamoya disease, and cerebral ischemia due to atherosclerosis and other vasculopathies.

In addition, he serves as the Director of the Cerebrovascular Research Laboratory which continues to be at the forefront of biomedical science, bringing the latest discoveries to the operating room and the patient bedside, to not only treat but also prevent stroke.

Dr. Connolly's special interests include brain aneurysms, arteriovenous malformations, carotid stenosis, EC- IC bypass for atheroocclusive disease and moyamoya, and surgical management of acute cerebrovascular emergencies.

  • Specialties

    Specialties

    Neurological Surgery

    Special Interests

    Society of Neurological Surgeons (President)
    Neurosurgical Society of America (President)
    Society of University Neurosurgeons (President)
    New York Neurosurgical Society (President)
    Joint Section of Cerebrovascular Surgery CNS/AANS (Chair)
    American Board of Neurological Surgery (Vice-Chair)
    American Association of Neurological Surgeons (President-Elect)
    American Academy of Neurological Surgery (President-Elect)
    National Residency Matching Program (Governance Committee, Board of Directors)
    New York State Neurosurgical Society (Board of Directors)
    American Board of Medical Specialties (Board of Directors)
    Stroke Council of the American Heart Association (Chair Brain-1 Study Section)
    American College of Surgeons (Advisory Council; Editor-in-chief, Neurosurgical Forum)
    Congress of Neurological Surgeons (Nominating Committee)
    American Society for Clinical Investigation

    Languages

    English
    Spanish

  • Education & Training

    Medical School

    Louisiana State University School of Medicine

    Internship

    New York Presbyterian Hospital/Columbia University

    Residency

    Columbia University Irving Medical Center

    Undergraduate

    Dartmouth College

  • Board Certifications & Affiliations

    Board Certifications

    American Board of Neurological Surgery - Neurological Surgery

Published Work

Pan H, Ho SE, Xue C, Cui J, Ross LS, Li F, Solomon RA, Connolly ES Jr, Reilly MP.

Atherosclerosis is a smooth muscle cell-driven tumor-like disease. bioRxiv [Preprint]. 2023 Mar 7:2023.

Carvalho Poyraz F, Boehme A, Cottarelli A, Eisler L, Elkind MSV, Ghoshal S, Agarwal S, Park S, Claassen J, Connolly ES, Hod EA, Roh DJ.

Red Blood Cell Transfusions Are Not Associated With Incident Complications or Poor Outcomes in Patients With Intracerebral Hemorrhage. J Am Heart Assoc. 2023 Jun 6;12(11):e028816.

Delgardo M, Tang AJ, Tudor T, Pascual-Leone A, Connolly ES Jr.

Role of gC1qR as a modulator of endothelial cell permeability and contributor to post-stroke inflammation and edema formation. Front Cell Neurosci. 2023 Jun 13;17:1123365.

Megjhani M, Terilli K, Weinerman B, Nametz D, Kwon SB, Velazquez A, Ghoshal S, Roh DJ, Agarwal S, Connolly ES Jr, Claassen J, Park S.

A Deep Learning Framework for Deriving Noninvasive Intracranial Pressure Waveforms from Transcranial Doppler. Ann Neurol. 2023 Jul;94(1):196-202.

Shinn G, Berger K, Roh D, Doyle K, Boehme AK, Connolly ES, Park S, Agarwal S, Claassen J, Der-Nigoghossian C.

Concordance Between Active Partial Thromboplastin Time and Anti-Factor Xa Assays in Neurocritically Ill Patients Receiving Subcutaneous Heparin Prophylaxis. Neurohospitalist. 2023 Jul;13(3):221-227.

Delgardo M, Rabin G, Tudor T, Tang AJ, Reeves G, Connolly ES.

Monitoring risk and preventing ischemic stroke in the very old. Expert Rev Neurother. 2023 Jul-Dec;23(9):791-801.

Megjhani M, Terilli K, Kwon SB, Nametz D, Weinerman B, Velazquez A, Ghoshal S, Roh D, Agarwal S, Connolly ES, Claassen J, Park S.

Automatic identification of intracranial pressure waveform during external ventricular drainage clamping: segmentation via wavelet analysis. Physiol Meas. 2023 Jul 4;44(6):10.1088/1361-6579.

Ironside N, Melmed K, Chen CJ, Omran S, Park S, Agarwal S, Connolly ES, Claassen J, Hod EA, Roh D.

ABO Blood Type and Thromboembolic Complications after Intracerebral Hemorrhage: an exploratory analysis. Res Sq [Preprint]. 2023 Jul 27:rs.3.rs-3108135.

Yoh N, Abou-Al-Shaar H, Bethamcharla R, Beiriger J, Mallela AN, Connolly ES, Sekula RF.

Minimally invasive surgical evacuation for spontaneous cerebellar hemorrhage: a case series and systematic review. Neurosurg Rev. 2023 Aug 23;46(1):208.

Sperring CP, Savage WM, Argenziano MG, Leifer VP, Alexander J, Echlov N, Spinazzi EF, Connolly ES Jr.

No-Reflow Post-Recanalization in Acute Ischemic Stroke: Mechanisms, Measurements, and Molecular Markers. Stroke. 2023 Sep;54(9):2472-2480.

Franzova E, Shen Q, Doyle K, Chen JM, Egbebike J, Vrosgou A, Carmona JC, Grobois L, Heinonen GA, Velazquez A, Gonzales IJ, Egawa S, Agarwal S, Roh D, Park S, Connolly ES, Claassen J.

Injury patterns associated with cognitive motor dissociation. Brain. 2023 Nov 2;146(11):4645-4658.

Tudor T, Spinazzi EF, Alexander JE, Mandigo GK, Lavine SD, Grinband J, Connolly ES Jr.

Progressive microvascular failure in acute ischemic stroke: A systematic review, meta-analysis, and time-course analysis. J Cereb Blood Flow Metab. 2023 Nov 28:271678X231216766.

Al-Dalahmah O, Sosunov AA, Sun Y, Liu Y, Madden N, Connolly ES, Troy CM, McKhann GM 2nd, Goldman JE.

The Matrix Receptor CD44 Is Present in Astrocytes throughout the Human Central Nervous System and Accumulates in Hypoxia and Seizures. Cells. 2024 Jan 10;13(2):129.

If You Are in Need of Emergency Care, Call 911.

The majority of the physicians on the Stamford Hospital Medical Staff are not employees or agents of the Hospital. They are independent practitioners who have been granted the privilege of using the Hospital's facilities for the care and treatment of their patients. This includes, but is not limited to, emergency department physicians, anesthesiologists, radiologists, surgeons, cardiologists, obstetricians, pathologists and other consultants who may treat patients.

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